Assessment of Macular Function by Multifocal Electroretinogram in Patients with Multiple Sclerosis Treated with Fingolimod

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Evaluation of the Incidence of Macular Edema in Patients with Multiple Sclerosis Treated with Fingolimod

Purpose: To determine the incidence of macular edema in patients with MS treated with 0.5 mg Fingolimod. Methods: In this prospective descriptive-analytic study a total of 115 patients were enrolled. Patients underwent an ophthalmologic examination before starting the treatment. In the fourth month after starting the treatment for each patient, regardless of whether or not being marked, the oph...

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Assessment of macular function by multifocal electroretinogram before and after macular hole surgery.

AIM To evaluate macular function before and after successful surgical closure of idiopathic macular holes using multifocal electroretinogram (ERG). METHODS 40 patients (40 eyes) with idiopathic macular holes were examined using multifocal ERG both before and after vitreous surgery. The postoperative period was from 1 to 12 months. RESULTS Preoperatively, the electrical retinal response dens...

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Cystoid macular edema associated with fingolimod use for multiple sclerosis.

Fingolimod is the first oral drug approved by the US Food and Drug Administration for multiple sclerosis (MS). It is a sphingosine-1phosphate–receptor modulator that prevents lymphocyte egress from lymph nodes and enhances astrocyte function. In this retrospective case series, 4 eyes from 3 patients developed cystoid macular edema (CME) after initiating fingolimod therapy. The study was approve...

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Comparing the Quality of Life in Patients With Multiple Sclerosis Consuming Fingolimod and CinnoVex

Background: Multiple Sclerosis (MS) is a chronic demyelinating, inflammatory, and degenerative disease of the central nervous system. MS gradually limits and deteriorates the patients’ quality of life. Objectives: This study aimed to evaluate and compare the quality of life in patients with MS consuming Fingolimod and CinnoVex. Materials & Methods: In an analytical cross-sectional study, 106 ...

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ژورنال

عنوان ژورنال: Advances in Therapy

سال: 2021

ISSN: 0741-238X,1865-8652

DOI: 10.1007/s12325-021-01728-4